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RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status
SIMPLE SUMMARY: PTEN is an important tumor suppressor that is frequently mutated in malignancy. PTEN mutational loss has been associated with reduced RAD51 expression and homologous recombination deficiency (HRD), however; recent studies have failed to recapitulate these findings. Here, we show that...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7693555/ https://ncbi.nlm.nih.gov/pubmed/33138032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113178 |
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