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High frequency of microsatellite instability and its substantial co-existence with KRAS and BRAF mutations in Vietnamese patients with colorectal cancer

Tumor heterogeneity and resistance to chemotherapy have been recognized as two major obstacles in the diagnosis and treatment of colorectal cancer (CRC). Microsatellite instability (MSI) and KRAS and BRAF mutations are common diagnostic factors that have been widely used to classify CRC for therapeu...

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Nguyen, Ha Thi, Le, Do Thanh, Duong, Quan Hong, Tatipamula, Vinay Bharadwaj, Van Nguyen, Bang
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693389/
https://ncbi.nlm.nih.gov/pubmed/33262833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12302
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