Clinical Utility of KRAS and BRAF Mutations in a Cohort of Patients With Colorectal Neoplasms Submitted for Microsatellite Instability Testing

BACKGROUND: Molecular analysis has become important in colorectal carcinoma (CRC) evaluation. Alterations in KRAS, BRAF, or mismatch repair (MMR) genes may determine therapeutic response or define a hereditary cancer syndrome. Correlation of DNA studies with clinical findings will further clarify th...

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Detaylı Bibliyografya
Asıl Yazarlar: Cushman-Vokoun, Allison M., Stover, Daniel G., Zhao, Zhiguo, Koehler, Elizabeth A., Berlin, Jordan D., Vnencak-Jones, Cindy L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090139/
https://ncbi.nlm.nih.gov/pubmed/23773459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2013.04.005
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