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Dynamics of Ligand Binding to a Rigid Glycosidase

The single‐domain GH11 glycosidase from Bacillus circulans (BCX) is involved in the degradation of hemicellulose, which is one of the most abundant renewable biomaterials in nature. We demonstrate that BCX in solution undergoes minimal structural changes during turnover. NMR spectroscopy results sho...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Ben Bdira, Fredj, Waudby, Christopher A., Volkov, Alexander N., Schröder, Sybrin P., AB, Eiso, Codée, Jeroen D. C., Overkleeft, Hermen S., Aerts, Johannes M. F. G., van Ingen, Hugo, Ubbink, Marcellus
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693232/
https://ncbi.nlm.nih.gov/pubmed/32533782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202003236
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