Artesunate Inhibits Growth of Sunitinib-Resistant Renal Cell Carcinoma Cells through Cell Cycle Arrest and Induction of Ferroptosis

SIMPLE SUMMARY: Renal cell carcinoma (RCC) is the most common kidney malignancy. Due to development of therapy resistance, efficacy of conventional drugs such as sunitinib is limited. Artesunate (ART), a drug originating from Traditional Chinese Medicine, has exhibited anti-tumor effects in several...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Markowitsch, Sascha D., Schupp, Patricia, Lauckner, Julia, Vakhrusheva, Olesya, Slade, Kimberly S., Mager, René, Efferth, Thomas, Haferkamp, Axel, Juengel, Eva
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692972/
https://ncbi.nlm.nih.gov/pubmed/33121039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113150
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