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Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

Oncogenic KRas reprograms pancreatic ductal adenocarcinoma (PDAC) cells to states which are highly resistant to apoptosis. Thus, a major preclinical goal is to identify effective strategies for killing PDAC cells. Artesunate (ART) is an anti-malarial that specifically induces programmed cell death i...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Eling, Nils, Reuter, Lukas, Hazin, John, Hamacher-Brady, Anne, Brady, Nathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468338/
https://ncbi.nlm.nih.gov/pubmed/26097885
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