Effects of the CB1 Receptor Antagonists AM6545 and AM4113 on Insulin Resistance in a High-Fructose High-Salt Rat Model of Metabolic Syndrome

Background and Objectives: Insulin resistance (IR) is a serious condition leading to development of diabetes and cardiovascular complications. Hyper-activation of cannabinoid receptors-1 (CB1) has been linked to the development of metabolic disorders such as IR. Therefore, the effect of blocking CB1...

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Veröffentlicht in:Medicina (Kaunas)
Hauptverfasser: Eid, Basma G., Neamatallah, Thikryat, Hanafy, Abeer, El-Bassossy, Hany M., Aldawsari, Hibah M., Vemuri, Kiran, Makriyannis, Alexandros
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692885/
https://ncbi.nlm.nih.gov/pubmed/33138155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina56110573
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