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Oral bioavailability of the novel cannabinoid CB1 antagonist AM6527: Effects on food-reinforced behavior and comparisons with AM4113

Drugs that interfere with cannabinoid CB1 transmission suppress food-motivated behaviors, and may be clinically useful as appetite suppressants. Several CB1 receptor inverse agonists, such as rimonabant and AM251, as well as the CB1 receptor neutral antagonist, AM4113, have been assessed for their e...

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Detalhes bibliográficos
Main Authors: Sink, K.S., Vemuri, V.K., Wood, J., Makriyannis, A., Salamone, J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806679/
https://ncbi.nlm.nih.gov/pubmed/18703081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.07.013
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