Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome

The role of cannabinoid receptors in nephropathy is gaining much attention. This study investigated the effects of two neutral CB1 receptor antagonists, AM6545 and AM4113, on nephropathy associated with metabolic syndrome (MetS). MetS was induced in rats by high-fructose high-salt feeding for 12 wee...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Molecules
Κύριοι συγγραφείς: Eid, Basma G., Neamatallah, Thikryat, Hanafy, Abeer, El-Bassossy, Hany M., Binmahfouz, Lenah, Aldawsari, Hibah M., Hasan, Atif, El-Aziz, Gamal Abd, Vemuri, Kiran, Makriyannis, Alexandros
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2021
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914730/
https://ncbi.nlm.nih.gov/pubmed/33562080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040866
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