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Development of Methods Derived from Iodine-Induced Specific Cleavage for Identification and Quantitation of DNA Phosphorothioate Modifications

DNA phosphorothioate (PT) modification is a novel modification that occurs on the DNA backbone, which refers to a non-bridging phosphate oxygen replaced by sulfur. This exclusive DNA modification widely distributes in bacteria but has not been found in eukaryotes to date. PT modification renders DNA...

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Библиографические подробности
Опубликовано в: :Biomolecules
Главные авторы: Zhu, Sucheng, Zheng, Tao, Kong, Lingxin, Li, Jinli, Cao, Bo, DeMott, Michael S., Sun, Yihua, Chen, Ying, Deng, Zixin, Dedon, Peter C., You, Delin
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692671/
https://ncbi.nlm.nih.gov/pubmed/33126637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10111491
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