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Novel Iodine-induced Cleavage Real-time PCR Assay for Accurate Quantification of Phosphorothioate Modified Sites in Bacterial DNA

DNA Phosphorothioate (PT), replacing a non-bridging phosphate oxygen atom with a sulfur atom, is one kind of common DNA modification in bacteria. Whole genome scale description of the location and frequency of PT modification is the key to understand its biological function. Herein we developed a no...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Yi, Zheng, Tao, Li, Jinli, Cui, Jinjie, Deng, Zixin, You, Delin, Yang, Litao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522622/
https://ncbi.nlm.nih.gov/pubmed/31097783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44011-x
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