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Interferon regulatory factor 4 deficiency in CD8(+) T cells abrogates terminal effector differentiation and promotes transplant acceptance
Allogeneic CD8(+) cytotoxic T cells play an essential role in rejecting transplanted allografts, but how their effector function is regulated on a transcriptional level remains unclear. Herein, we investigate the role of interferon regulatory factor 4 (IRF4) in controlling CD8(+) T‐cell function in...
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| Publicado no: | Immunology |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7692246/ https://ncbi.nlm.nih.gov/pubmed/32892353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13258 |
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