Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation

Upon infection, CD8(+) T cells undergo a stepwise process of early activation, expansion and differentiation into effector cells. How these phases are transcriptionally regulated is incompletely defined. Here, we report that interferon regulatory factor 4 (IRF4), dispensable for early CD8(+) T cell...

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Detalhes bibliográficos
Principais autores: Yao, Shuyu, Buzo, Bruno Fernando d., Pham, Duy, Jiang, Li, Taparowsky, Elizabeth J., Kaplan, Mark H., Sun, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855863/
https://ncbi.nlm.nih.gov/pubmed/24211184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.10.007
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