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KLF4 Regulates Goblet Cell Differentiation in BMI1(+) Reserve Intestinal Stem Cell Lineage during Homeostasis

Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor, expressed in villus cells of the intestinal epithelium, that promotes cellular differentiation and tissue homeostasis. Previous studies suggest that BMI1(+) cells represent secretory progenitors with reserve intestinal stem cell (rI...

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Detalhes bibliográficos
Publicado no:Int J Stem Cells
Main Authors: Katano, Takahito, Bialkowska, Agnieszka B., Yang, Vincent W.
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Stem Cell Research 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691855/
https://ncbi.nlm.nih.gov/pubmed/32840226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc20048
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