Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells

BACKGROUND & AIMS: Self-renewal and multipotent differentiation are cardinal properties of intestinal stem cells (ISCs), mediated in part by WNT and NOTCH signaling. Although these pathways are well characterized, the molecular mechanisms that control the ‘stemness’ of ISCs are still not well de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Gastroenterol Hepatol
Prif Awduron: Kim, Chang-Kyung, Saxena, Madhurima, Maharjan, Kasmika, Song, Jane J., Shroyer, Kenneth R., Bialkowska, Agnieszka B., Shivdasani, Ramesh A., Yang, Vincent W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078555/
https://ncbi.nlm.nih.gov/pubmed/31778829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.11.009
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