Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells

BACKGROUND & AIMS: Self-renewal and multipotent differentiation are cardinal properties of intestinal stem cells (ISCs), mediated in part by WNT and NOTCH signaling. Although these pathways are well characterized, the molecular mechanisms that control the ‘stemness’ of ISCs are still not well de...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Kim, Chang-Kyung, Saxena, Madhurima, Maharjan, Kasmika, Song, Jane J., Shroyer, Kenneth R., Bialkowska, Agnieszka B., Shivdasani, Ramesh A., Yang, Vincent W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078555/
https://ncbi.nlm.nih.gov/pubmed/31778829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.11.009
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