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Interplay among p21(Waf1/Cip1), MUSASHI-1 and Krüppel-like factor 4 in activation of Bmi1-Cre(ER) reserve intestinal stem cells after gamma radiation-induced injury

Gamma radiation is a commonly used adjuvant treatment for abdominally localized cancer. Since its therapeutic potential is limited due to gastrointestinal (GI) syndrome, elucidation of the regenerative response following radiation-induced gut injury is needed to develop a preventive treatment. Previ...

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Publicat a:Sci Rep
Autors principals: Orzechowska, Emilia J., Katano, Takahito, Bialkowska, Agnieszka B., Yang, Vincent W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591575/
https://ncbi.nlm.nih.gov/pubmed/33110120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75171-w
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