The Gut-enriched Krüppel-like Factor (Krüppel-like Factor 4) Mediates the Transactivating Effect of p53 on the p21(WAF1/Cip1) Promoter

An important mechanism by which the tumor suppressor p53 maintains genomic stability is to induce cell cycle arrest through activation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene. We show that the gene encoding the gut-enriched Krüppel-like factor (GKLF, KLF4) is concurrently induce...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhang, Weiqing, Geiman, Deborah E., Shields, Janiel M., Dang, Duyen T., Mahatan, Channing S., Kaestner, Klaus H., Biggs, Joseph R., Kraft, Andrew S., Yang, Vincent W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231805/
https://ncbi.nlm.nih.gov/pubmed/10749849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C000062200
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares