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The Poly-E motif in Titin's PEVK region undergoes pH dependent conformational changes

The muscle protein titin plays a crucial role in passive elasticity and the disordered PEVK region within titin is central to that function. The PEVK region is so named due to its high proline, glutamate, valine and lysine content and the high charge density in this region results in a lack of organ...

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Dades bibliogràfiques
Publicat a:Biochem Biophys Rep
Autors principals: Sudarshi Premawardhana, Dassanayake Mudiyanselage, Zhang, Fang, Xu, Jin, Gage, Matthew J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691732/
https://ncbi.nlm.nih.gov/pubmed/33294637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100859
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