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A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs)

Fewer females develop AADs (ascending aortic aneurysms and dissections) and the reasons for this protection remain poorly understood. The present study seeks to develop a mouse model that may be utilized to address this sexual dimorphism. Adult normolipidemic mice were challenged with BAPN (β‐aminop...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Main Authors: Qi, Xiaoyan, Wang, Fen, Chun, Changzoon, Saldarriaga, Lennon, Jiang, Zhisheng, Pruitt, Eric Y., Arnaoutakis, George J., Upchurch, Gilbert R., Jiang, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690909/
https://ncbi.nlm.nih.gov/pubmed/33242364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14631
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