A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs)

Fewer females develop AADs (ascending aortic aneurysms and dissections) and the reasons for this protection remain poorly understood. The present study seeks to develop a mouse model that may be utilized to address this sexual dimorphism. Adult normolipidemic mice were challenged with BAPN (β‐aminop...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Qi, Xiaoyan, Wang, Fen, Chun, Changzoon, Saldarriaga, Lennon, Jiang, Zhisheng, Pruitt, Eric Y., Arnaoutakis, George J., Upchurch, Gilbert R., Jiang, Zhihua
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690909/
https://ncbi.nlm.nih.gov/pubmed/33242364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14631
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