A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs)

Fewer females develop AADs (ascending aortic aneurysms and dissections) and the reasons for this protection remain poorly understood. The present study seeks to develop a mouse model that may be utilized to address this sexual dimorphism. Adult normolipidemic mice were challenged with BAPN (β‐aminop...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Qi, Xiaoyan, Wang, Fen, Chun, Changzoon, Saldarriaga, Lennon, Jiang, Zhisheng, Pruitt, Eric Y., Arnaoutakis, George J., Upchurch, Gilbert R., Jiang, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690909/
https://ncbi.nlm.nih.gov/pubmed/33242364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14631
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