Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells

Glioblastoma (GBM) is the most prevalent malignant primary brain tumor with a very poor survival rate. Temozolomide (TMZ) is the common chemotherapeutic agent used for GBM treatment. We recently demonstrated that simvastatin (Simva) increases TMZ-induced apoptosis via the inhibition of autophagic fl...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Dastghaib, Sanaz, Shojaei, Shahla, Mostafavi-Pour, Zohreh, Sharma, Pawan, Patterson, John B., Samali, Afshin, Mokarram, Pooneh, Ghavami, Saeid
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690447/
https://ncbi.nlm.nih.gov/pubmed/33105603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112339
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires