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Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis

Glutathione (GSH) plays a central role in the redox balance maintenance in mammalian cells. Previous studies of industrial Chinese hamster ovary cell lines have demonstrated a relationship between GSH metabolism and clone productivity. However, a thorough investigation is required to understand this...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Bioeng
Hauptverfasser: Chevallier, Valentine, Schoof, Erwin M., Malphettes, Laetitia, Andersen, Mikael R., Workman, Christopher T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689765/
https://ncbi.nlm.nih.gov/pubmed/32662871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27495
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