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Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis

Glutathione (GSH) plays a central role in the redox balance maintenance in mammalian cells. Previous studies of industrial Chinese hamster ovary cell lines have demonstrated a relationship between GSH metabolism and clone productivity. However, a thorough investigation is required to understand this...

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Bibliografiske detaljer
Udgivet i:Biotechnol Bioeng
Main Authors: Chevallier, Valentine, Schoof, Erwin M., Malphettes, Laetitia, Andersen, Mikael R., Workman, Christopher T.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689765/
https://ncbi.nlm.nih.gov/pubmed/32662871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27495
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