Antiproliferative Activity of Functionalized Histidine‐derived Au(I) bis‐NHC Complexes for Bioconjugation

A series of histidine derived Au(I) bis‐NHC complexes bearing different ester, amide and carboxylic acid functionalities as well as wingtip substituents is synthesized and characterized. The stability in aqueous media, in vitro cytotoxicity in a set of cancer cell lines (MCF7, PC3 and A2780/A2780cis...

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Publicat a:Chem Asian J
Autors principals: Jakob, Christian H. G., Dominelli, Bruno, Hahn, Eva M., Berghausen, Tobias O., Pinheiro, Teresa, Marques, Fernanda, Reich, Robert M., Correia, João D. G., Kühn, Fritz E.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689731/
https://ncbi.nlm.nih.gov/pubmed/32592289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/asia.202000620
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