Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model

BACKGROUND: Well-characterized preclinical models are essential for immune-oncology research. We investigated the feasibility of our humanized mouse model for evaluating the long-term efficacy of immunotherapy and biomarkers. METHODS: Humanized mice were generated by injecting human fetal cord blood...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Park, Nahee, Pandey, Kamal, Chang, Sei Kyung, Kwon, Ah-Young, Cho, Young Bin, Hur, Jin, Katwal, Nar Bahadur, Kim, Seung Ki, Lee, Seung Ah, Son, Gun Woo, Jo, Jong Min, Ahn, Hee Jung, Moon, Yong Wha
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689593/
https://ncbi.nlm.nih.gov/pubmed/33239416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001513
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