Synergism of AZD6738, an ATR Inhibitor, in Combination with Belotecan, a Camptothecin Analogue, in Chemotherapy-Resistant Ovarian Cancer

Epithelial ovarian cancer remains the leading cause of mortality among all gynecologic malignancies owing to recurrence and ultimate development of chemotherapy resistance in the majority of patients. In the chemotherapy-resistant ovarian cancer preclinical model, we investigated whether AZD6738 (an...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Hur, Jin, Ghosh, Mithun, Kim, Tae Heon, Park, Nahee, Pandey, Kamal, Cho, Young Bin, Hong, Sa Deok, Katuwal, Nar Bahadur, Kang, Minsil, An, Hee Jung, Moon, Yong Wha
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865398/
https://ncbi.nlm.nih.gov/pubmed/33513721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031223
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