Deregulated Immune Pathway Associated with Palbociclib Resistance in Preclinical Breast Cancer Models: Integrative Genomics and Transcriptomics

Recently, cyclin-dependent kinase (CDK) 4/6 inhibitors have been widely used to treat advanced hormone receptor-positive breast cancer. Despite promising clinical outcomes, almost all patients eventually acquire resistance to CDK4/6 inhibitors. Here, we screened genes associated with palbociclib res...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Pandey, Kamal, Lee, Eunbyeol, Park, Nahee, Hur, Jin, Cho, Young Bin, Katuwal, Nar Bahadur, Kim, Seung Ki, Lee, Seung Ah, Kim, Isaac, An, Hee Jung, Hwang, Sohyun, Moon, Yong Wha
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912104/
https://ncbi.nlm.nih.gov/pubmed/33504001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12020159
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