Carregant...
Pharmacological clearance of misfolded rhodopsin for the treatment of RHO-associated retinitis pigmentosa.
Rhodopsin mutation and misfolding is a common cause of autosomal dominant retinitis pigmentosa. Using a luciferase reporter assay, we undertook a small-molecule high-throughput screening of 68,979 compounds and identified nine compounds that selectively reduced the misfolded P23H rhodopsin without a...
Guardat en:
| Publicat a: | FASEB J |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7688577/ https://ncbi.nlm.nih.gov/pubmed/32536017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000282R |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|