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Protein-avoidant ionic liquid (PAIL)–coated nanoparticles to increase bloodstream circulation and drive biodistribution

The rapid clearance of intravenously administered nanoparticles (NPs) from the bloodstream is a major unsolved problem in nanomedicine. Here, we describe the first use of biocompatible protein-avoidant ionic liquids (PAILs) as NP surface modifiers to reduce opsonization. An ionic liquid choline hexe...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Hamadani, Christine M., Goetz, Morgan J., Mitragotri, Samir, Tanner, Eden E. L.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688330/
https://ncbi.nlm.nih.gov/pubmed/33239302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd7563
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