Effect of structural stability on endolysosomal degradation and T‐cell reactivity of major shrimp allergen tropomyosin

BACKGROUND: Tropomyosins are highly conserved proteins, an attribute that forms the molecular basis for their IgE antibody cross‐reactivity. Despite sequence similarities, their allergenicity varies greatly between ingested and inhaled invertebrate sources. In this study, we investigated the relatio...

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Veröffentlicht in:Allergy
Hauptverfasser: Kamath, Sandip D., Scheiblhofer, Sandra, Johnson, Christopher M., Machado, Yoan, McLean, Thomas, Taki, Aya C., Ramsland, Paul A., Iyer, Swati, Joubert, Isabella, Hofer, Heidi, Wallner, Michael, Thalhamer, Josef, Rolland, Jennifer, O’Hehir, Robyn, Briza, Peter, Ferreira, Fatima, Weiss, Richard, Lopata, Andreas L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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ORIGINAL ARTICLES
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687109/
https://ncbi.nlm.nih.gov/pubmed/32436591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14410
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