Development of Biarylalkyl Carboxylic Acid Amides with Improved Anti‐schistosomal Activity

The parasitic disease schistosomiasis is the cause of more than 200 000 human deaths per year. Although the disease is treatable, there is one major shortcoming: praziquantel has been the only drug used to combat these parasites since 1977. The risk of the emergence of resistant schistosomes is know...

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Pubblicato in:ChemMedChem
Autori principali: Peter Ventura, Alejandra M., Haeberlein, Simone, Lange‐Grünweller, Kerstin, Grünweller, Arnold, Hartmann, Roland K., Grevelding, Christoph G., Schlitzer, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687077/
https://ncbi.nlm.nih.gov/pubmed/31454168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900423
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