Dexmedetomidine Pharmacokinetics and a New Dosing Paradigm in Infants Supported With Cardiopulmonary Bypass

BACKGROUND: Dexmedetomidine is increasingly used off-label in infants and children with cardiac disease during cardiopulmonary bypass (CPB) and in the postoperative period. Despite its frequent use, optimal dosing of dexmedetomidine in the setting of CPB has not been identified but is expected to di...

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Pubblicato in:Anesth Analg
Autori principali: Zimmerman, Kanecia O., Wu, Huali, Laughon, Matthew, Greenberg, Rachel G., Walczak, Richard, Schulman, Scott R., Smith, P. Brian, Hornik, Christoph P., Cohen-Wolkowiez, Michael, Watt, Kevin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687048/
https://ncbi.nlm.nih.gov/pubmed/31743171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000003700
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