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Population Pharmacokinetics of Dexmedetomidine in Infants

Despite limited pharmacokinetic (PK) data, dexmedetomidine is increasingly being used off-label for sedation in infants. We aimed to characterize the developmental PK changes of dexmedetomidine during infancy. In this open-label, single-center PK study of dexmedetomidine in infants receiving dexmede...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Greenberg, Rachel G., Wu, Huali, Laughon, Matthew, Capparelli, Edmund, Rowe, Stevie, Zimmerman, Kanecia O., Smith, P. Brian, Cohen-Wolkowiez, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561462/
https://ncbi.nlm.nih.gov/pubmed/28444697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.904
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