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MFGE8 is down‐regulated in cardiac fibrosis and attenuates endothelial‐mesenchymal transition through Smad2/3‐Snail signalling pathway

Endothelial‐mesenchymal transition (EndMT) is a major source of transformed cardiac fibroblasts, which is reported to play a key role in cardiac fibrosis (CF), a pathogenesis of cardiovascular diseases such as heart failure, myocardial infarction and atrial fibrillation. Nonetheless, the specific me...

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Опубликовано в: :J Cell Mol Med
Главные авторы: Wang, Bo, Ge, Zhuowang, Wu, Yan, Zha, Yafang, Zhang, Xuan, Yan, Yexiang, Xie, Yuquan
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686985/
https://ncbi.nlm.nih.gov/pubmed/32945126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15871
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