Puerarin Protects against Cardiac Fibrosis Associated with the Inhibition of TGF-β1/Smad2-Mediated Endothelial-to-Mesenchymal Transition

BACKGROUND: Puerarin is a kind of flavonoids and is extracted from Chinese herb Kudzu root. Puerarin is widely used as an adjuvant therapy in Chinese clinics. But little is known about its effects on regulating cardiac fibrosis. METHODS: Mice were subjected to transverse aorta constriction (TAC) for...

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Veröffentlicht in:PPAR Res
Hauptverfasser: Jin, Ya-Ge, Yuan, Yuan, Wu, Qing-Qing, Zhang, Ning, Fan, Di, Che, Yan, Wang, Zhao-Peng, Xiao, Yang, Wang, Sha-Sha, Tang, Qi-Zhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468594/
https://ncbi.nlm.nih.gov/pubmed/28638404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2647129
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