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Transforming Growth Factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling

Endothelial-mesenchymal transition (EndMT) is a critical process of cardiac development and disease progression. However, little is know about the signaling mechanisms that cause endothelial cells to transform into mesenchymal cells. Here we show that transforming growth factor-beta2 (TGF-β2) stimul...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochem J
Main Authors: Medici, Damian, Potenta, Scott, Kalluri, Raghu
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457510/
https://ncbi.nlm.nih.gov/pubmed/21585337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101500
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