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Transforming Growth Factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling

Endothelial-mesenchymal transition (EndMT) is a critical process of cardiac development and disease progression. However, little is know about the signaling mechanisms that cause endothelial cells to transform into mesenchymal cells. Here we show that transforming growth factor-beta2 (TGF-β2) stimul...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Medici, Damian, Potenta, Scott, Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457510/
https://ncbi.nlm.nih.gov/pubmed/21585337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101500
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