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Transforming Growth Factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling

Endothelial-mesenchymal transition (EndMT) is a critical process of cardiac development and disease progression. However, little is know about the signaling mechanisms that cause endothelial cells to transform into mesenchymal cells. Here we show that transforming growth factor-beta2 (TGF-β2) stimul...

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Podrobná bibliografie
Vydáno v:Biochem J
Hlavní autoři: Medici, Damian, Potenta, Scott, Kalluri, Raghu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457510/
https://ncbi.nlm.nih.gov/pubmed/21585337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101500
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