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Transforming Growth Factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling

Endothelial-mesenchymal transition (EndMT) is a critical process of cardiac development and disease progression. However, little is know about the signaling mechanisms that cause endothelial cells to transform into mesenchymal cells. Here we show that transforming growth factor-beta2 (TGF-β2) stimul...

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Bibliografiske detaljer
Udgivet i:Biochem J
Main Authors: Medici, Damian, Potenta, Scott, Kalluri, Raghu
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457510/
https://ncbi.nlm.nih.gov/pubmed/21585337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101500
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