A new role of glutathione peroxidase 4 during human erythroblast enucleation

The selenoprotein glutathione peroxidase 4 (GPX4), the only member of the glutathione peroxidase family able to directly reduce cell membrane–oxidized fatty acids and cholesterol, was recently identified as the central regulator of ferroptosis. GPX4 knockdown in mouse hematopoietic cells leads to he...

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Vydáno v:Blood Adv
Hlavní autoři: Ouled-Haddou, Hakim, Messaoudi, Kahia, Demont, Yohann, Lopes dos Santos, Rogiéro, Carola, Candice, Caulier, Alexis, Vong, Pascal, Jankovsky, Nicolas, Lebon, Delphine, Willaume, Alexandre, Demagny, Julien, Boyer, Thomas, Marolleau, Jean-Pierre, Rochette, Jacques, Garçon, Loïc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2020
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686909/
https://ncbi.nlm.nih.gov/pubmed/33211827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003100
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