A new role of glutathione peroxidase 4 during human erythroblast enucleation

The selenoprotein glutathione peroxidase 4 (GPX4), the only member of the glutathione peroxidase family able to directly reduce cell membrane–oxidized fatty acids and cholesterol, was recently identified as the central regulator of ferroptosis. GPX4 knockdown in mouse hematopoietic cells leads to he...

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Ouled-Haddou, Hakim, Messaoudi, Kahia, Demont, Yohann, Lopes dos Santos, Rogiéro, Carola, Candice, Caulier, Alexis, Vong, Pascal, Jankovsky, Nicolas, Lebon, Delphine, Willaume, Alexandre, Demagny, Julien, Boyer, Thomas, Marolleau, Jean-Pierre, Rochette, Jacques, Garçon, Loïc
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2020
Teme:
Red Cells, Iron, and Erythropoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686909/
https://ncbi.nlm.nih.gov/pubmed/33211827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003100
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