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Complex fibroblast response to glucocorticoids may underlie variability of clinical efficacy in the vocal folds

Similar to the hypertrophic scar and keloids, the efficacy of glucorticoids (GC) for vocal fold injury is highly variable. We previously reported dexamethasone enhanced the pro-fibrotic effects of transforming growth factor (TGF)-β as a potential mechanism for inconsistent clinical outcomes. In the...

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Pubblicato in:Sci Rep
Autori principali: Nakamura, Ryosuke, Mukudai, Shigeyuki, Bing, Renjie, Garabedian, Michael J., Branski, Ryan C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686477/
https://ncbi.nlm.nih.gov/pubmed/33235235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77445-9
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