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Complex fibroblast response to glucocorticoids may underlie variability of clinical efficacy in the vocal folds

Similar to the hypertrophic scar and keloids, the efficacy of glucorticoids (GC) for vocal fold injury is highly variable. We previously reported dexamethasone enhanced the pro-fibrotic effects of transforming growth factor (TGF)-β as a potential mechanism for inconsistent clinical outcomes. In the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakamura, Ryosuke, Mukudai, Shigeyuki, Bing, Renjie, Garabedian, Michael J., Branski, Ryan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686477/
https://ncbi.nlm.nih.gov/pubmed/33235235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77445-9
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