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Enantioselective Intramolecular Allylic Substitution via Synergistic Palladium/Chiral Phosphoric Acid Catalysis: Insight into Stereoinduction through Statistical Modeling

The mode of asymmetric induction in an enantioselective intramolecular allylic substitution reaction catalyzed by a combination of palladium and a chiral phosphoric acid was investigated by a combined experimental and statistical modeling approach. Experiments to probe nonlinear effects, the reactiv...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Tsai, Cheng-Che, Sandford, Christopher, Wu, Tao, Chen, Buyun, Sigman, Matthew S., Toste, F. Dean
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686151/
https://ncbi.nlm.nih.gov/pubmed/32453890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006237
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