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Enantioselective Intramolecular Allylic Substitution via Synergistic Palladium/Chiral Phosphoric Acid Catalysis: Insight into Stereoinduction through Statistical Modeling

The mode of asymmetric induction in an enantioselective intramolecular allylic substitution reaction catalyzed by a combination of palladium and a chiral phosphoric acid was investigated by a combined experimental and statistical modeling approach. Experiments to probe nonlinear effects, the reactiv...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Tsai, Cheng-Che, Sandford, Christopher, Wu, Tao, Chen, Buyun, Sigman, Matthew S., Toste, F. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686151/
https://ncbi.nlm.nih.gov/pubmed/32453890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006237
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