Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions

Human induced pluripotent stem cell (hiPSC)‐derived blood‐brain barrier (BBB) models established to date lack expression of key adhesion molecules involved in immune cell migration across the BBB in vivo. Here, we introduce the extended endothelial cell culture method (EECM), which differentiates hi...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Nishihara, Hideaki, Gastfriend, Benjamin D., Soldati, Sasha, Perriot, Sylvain, Mathias, Amandine, Sano, Yasuteru, Shimizu, Fumitaka, Gosselet, Fabien, Kanda, Takashi, Palecek, Sean P., Du Pasquier, Renaud, Shusta, Eric V., Engelhardt, Britta
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686106/
https://ncbi.nlm.nih.gov/pubmed/33124083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001507RR
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