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Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection

After over 3 decades of research, an effective anti-HIV vaccine remains elusive. The recently halted HVTN702 clinical trial not only further stresses the challenge to develop an effective HIV vaccine but also emphasizes that unconventional and novel vaccine strategies are urgently needed. Here, we r...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Li, Hongzhao, Omange, Robert W., Liang, Binhua, Toledo, Nikki, Hai, Yan, Liu, Lewis R., Schalk, Dane, Crecente-Campo, Jose, Dacoba, Tamara G., Lambe, Andrew B., Lim, So-Yon, Li, Lin, Kashem, Mohammad Abul, Wan, Yanmin, Correia-Pinto, Jorge F., Seaman, Michael S., Liu, Xiao Qing, Balshaw, Robert F., Li, Qingsheng, Schultz-Darken, Nancy, Alonso, Maria J., Plummer, Francis A., Whitney, James B., Luo, Ma
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685735/
https://ncbi.nlm.nih.gov/pubmed/32853182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138728
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