Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection

After over 3 decades of research, an effective anti-HIV vaccine remains elusive. The recently halted HVTN702 clinical trial not only further stresses the challenge to develop an effective HIV vaccine but also emphasizes that unconventional and novel vaccine strategies are urgently needed. Here, we r...

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Udgivet i:J Clin Invest
Main Authors: Li, Hongzhao, Omange, Robert W., Liang, Binhua, Toledo, Nikki, Hai, Yan, Liu, Lewis R., Schalk, Dane, Crecente-Campo, Jose, Dacoba, Tamara G., Lambe, Andrew B., Lim, So-Yon, Li, Lin, Kashem, Mohammad Abul, Wan, Yanmin, Correia-Pinto, Jorge F., Seaman, Michael S., Liu, Xiao Qing, Balshaw, Robert F., Li, Qingsheng, Schultz-Darken, Nancy, Alonso, Maria J., Plummer, Francis A., Whitney, James B., Luo, Ma
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685735/
https://ncbi.nlm.nih.gov/pubmed/32853182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138728
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