Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection

After over 3 decades of research, an effective anti-HIV vaccine remains elusive. The recently halted HVTN702 clinical trial not only further stresses the challenge to develop an effective HIV vaccine but also emphasizes that unconventional and novel vaccine strategies are urgently needed. Here, we r...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Li, Hongzhao, Omange, Robert W., Liang, Binhua, Toledo, Nikki, Hai, Yan, Liu, Lewis R., Schalk, Dane, Crecente-Campo, Jose, Dacoba, Tamara G., Lambe, Andrew B., Lim, So-Yon, Li, Lin, Kashem, Mohammad Abul, Wan, Yanmin, Correia-Pinto, Jorge F., Seaman, Michael S., Liu, Xiao Qing, Balshaw, Robert F., Li, Qingsheng, Schultz-Darken, Nancy, Alonso, Maria J., Plummer, Francis A., Whitney, James B., Luo, Ma
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685735/
https://ncbi.nlm.nih.gov/pubmed/32853182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138728
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