Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection

After over 3 decades of research, an effective anti-HIV vaccine remains elusive. The recently halted HVTN702 clinical trial not only further stresses the challenge to develop an effective HIV vaccine but also emphasizes that unconventional and novel vaccine strategies are urgently needed. Here, we r...

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Publicado en:J Clin Invest
Main Authors: Li, Hongzhao, Omange, Robert W., Liang, Binhua, Toledo, Nikki, Hai, Yan, Liu, Lewis R., Schalk, Dane, Crecente-Campo, Jose, Dacoba, Tamara G., Lambe, Andrew B., Lim, So-Yon, Li, Lin, Kashem, Mohammad Abul, Wan, Yanmin, Correia-Pinto, Jorge F., Seaman, Michael S., Liu, Xiao Qing, Balshaw, Robert F., Li, Qingsheng, Schultz-Darken, Nancy, Alonso, Maria J., Plummer, Francis A., Whitney, James B., Luo, Ma
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685735/
https://ncbi.nlm.nih.gov/pubmed/32853182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138728
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