Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma

BACKGROUND: Patients with diffuse midline gliomas (DMGs), including diffuse intrinsic pontine glioma (DIPG), have dismal outcomes. We previously described the H3.3K27M mutation as a shared neoantigen in HLA-A*02.01(+), H3.3K27M(+) DMGs. Within the Pacific Pediatric Neuro-Oncology Consortium, we asse...

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Udgivet i:J Clin Invest
Main Authors: Mueller, Sabine, Taitt, Jared M., Villanueva-Meyer, Javier E., Bonner, Erin R., Nejo, Takahide, Lulla, Rishi R., Goldman, Stewart, Banerjee, Anu, Chi, Susan N., Whipple, Nicholas S., Crawford, John R., Gauvain, Karen, Nazemi, Kellie J., Watchmaker, Payal B., Almeida, Neil D., Okada, Kaori, Salazar, Andres M., Gilbert, Ryan D., Nazarian, Javad, Molinaro, Annette M., Butterfield, Lisa H., Prados, Michael D., Okada, Hideho
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685729/
https://ncbi.nlm.nih.gov/pubmed/32817593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140378
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