Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma

BACKGROUND: Patients with diffuse midline gliomas (DMGs), including diffuse intrinsic pontine glioma (DIPG), have dismal outcomes. We previously described the H3.3K27M mutation as a shared neoantigen in HLA-A*02.01(+), H3.3K27M(+) DMGs. Within the Pacific Pediatric Neuro-Oncology Consortium, we asse...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Mueller, Sabine, Taitt, Jared M., Villanueva-Meyer, Javier E., Bonner, Erin R., Nejo, Takahide, Lulla, Rishi R., Goldman, Stewart, Banerjee, Anu, Chi, Susan N., Whipple, Nicholas S., Crawford, John R., Gauvain, Karen, Nazemi, Kellie J., Watchmaker, Payal B., Almeida, Neil D., Okada, Kaori, Salazar, Andres M., Gilbert, Ryan D., Nazarian, Javad, Molinaro, Annette M., Butterfield, Lisa H., Prados, Michael D., Okada, Hideho
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Clinical Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685729/
https://ncbi.nlm.nih.gov/pubmed/32817593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140378
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