ALK-transformed mature T lymphocytes restore early thymus progenitor features

Anaplastic large cell lymphoma (ALCL) is a mature T cell neoplasm that often expresses the CD4(+) T cell surface marker. It usually harbors the t(2;5) (p23;q35) translocation, leading to the ectopic expression of NPM-ALK, a chimeric tyrosine kinase. We demonstrated that in vitro transduction of norm...

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Vydáno v:J Clin Invest
Hlavní autoři: Congras, Annabelle, Hoareau-Aveilla, Coralie, Caillet, Nina, Tosolini, Marie, Villarese, Patrick, Cieslak, Agata, Rodriguez, Laura, Asnafi, Vahid, Macintyre, Elisabeth, Egger, Gerda, Brousset, Pierre, Lamant, Laurence, Meggetto, Fabienne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685726/
https://ncbi.nlm.nih.gov/pubmed/33141118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134990
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