Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth

The regulatory microRNA miR-150 is involved in the development of hemopathies and is downregulated in T-lymphomas, such as anaplastic large-cell lymphoma (ALCL) tumors. ALCL is defined by the presence or absence of translocations that activate the anaplastic lymphoma kinase (ALK), with nucleophosmin...

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Vydáno v:J Clin Invest
Hlavní autoři: Hoareau-Aveilla, Coralie, Valentin, Thibaud, Daugrois, Camille, Quelen, Cathy, Mitou, Géraldine, Quentin, Samuel, Jia, Jinsong, Spicuglia, Salvatore, Ferrier, Pierre, Ceccon, Monica, Giuriato, Sylvie, Gambacorti-Passerini, Carlo, Brousset, Pierre, Lamant, Laurence, Meggetto, Fabienne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588301/
https://ncbi.nlm.nih.gov/pubmed/26258416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78488
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